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Peg3 Gene Detail
Summary
  • Symbol
    Peg3
  • Name
    paternally expressed 3
  • Synonyms
    End4, Gcap4, Pw1, Zfp102
  • Feature Type
    protein coding gene
  • IDs
    MGI:104748
    NCBI Gene: 18616
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:6706891-6733430 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 3.89 cM, cytoband A2-B1
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    495 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    2
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104748
 protein coding gene Chr7:6706891-6733443 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031614
 protein coding gene Chr7:3801450-3827979 (-)
A/J MGP_AJ_G0031588
 protein coding gene Chr7:3696050-3722579 (-)
AKR/J MGP_AKRJ_G0031515
 protein coding gene Chr7:3939336-3965854 (-)
BALB/cJ MGP_BALBcJ_G0031596
 protein coding gene Chr7:3803120-3829649 (-)
C3H/HeJ MGP_C3HHeJ_G0031317
 protein coding gene Chr7:3780250-3806782 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032059
 protein coding gene Chr7:4010910-4037439 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029172
 protein coding gene Chr7:3380341-3406758 (-)
CAST/EiJ MGP_CASTEiJ_G0030679
 protein coding gene Chr7:3661646-3689519 (-)
CBA/J MGP_CBAJ_G0031274
 protein coding gene Chr7:4159937-4186466 (-)
DBA/2J MGP_DBA2J_G0031432
 protein coding gene Chr7:3730597-3757127 (-)
FVB/NJ MGP_FVBNJ_G0031386
 protein coding gene Chr7:3702190-3728704 (-)
LP/J MGP_LPJ_G0031518
 protein coding gene Chr7:3935402-3961929 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031425
 protein coding gene Chr7:4144448-4171293 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032088
 protein coding gene Chr7:3726026-3752558 (-)
PWK/PhJ MGP_PWKPhJ_G0030406
 protein coding gene Chr7:3881376-3908061 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030233
 protein coding gene Chr7:3313131-3339727 (-)
WSB/EiJ MGP_WSBEiJ_G0030773
 protein coding gene Chr7:3877989-3904499 (-)



Homology
more
  • Human Ortholog
    PEG3, paternally expressed 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEG3, paternally expressed 3
  • Synonyms
    PW1, ZKSCAN22, ZNF904, ZSCAN24
  • Links
    NCBI Gene ID: 5178
    neXtProt AC: NX_Q9GZU2
    UniProt: Q9GZU2

  • Chr Location
    19q13.43; chr19:56810077-56840728 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 3 alleles in 3 genetic backgrounds
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygous mutant females exhibit growth retardation, impaired maternal behavior and diminished milk ejection, and fewer oxytocin neurons.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1065
  • Tissues
    213
  • cDNA Data
    40
  • Literature Summary
    60
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000002265 Ensembl Gene Model | MGI Sequence Detail 26540 C57BL/6J ±  kb
    transcript ENSMUST00000239104 Ensembl | MGI Sequence Detail 8986 Not Applicable  
    polypeptide ENSMUSP00000159154 Ensembl | MGI Sequence Detail 1632 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 74
      Genomic 13
      cDNA 41
      Primer pair 16
      Other 4

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGD-MRK-18675, MGD-MRK-28039, MGD-MRK-36316, MGI:101851, MGI:107740, MGI:2142084, MGI:2662734
    References
    more
    • Summaries
      All 132
      Developmental Gene Expression 60
      Gene Ontology 6
      Phenotypes 30
    • Earliest
      J:19885 Kambouris M, et al., Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. Brain Res Mol Brain Res. 1994 Sep;25(3-4):183-91
    • Latest
      J:342617 Dali O, et al., Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory